WB analysis of schwann cells from embryonic knockout mice, adult human nerves, and neonatal rat nerves using GTX30208 Neurofibromin antibody [McNFn27a].
![IHC-P analysis of human brain tissue using GTX30208 Neurofibromin antibody [McNFn27a]. Dilution : 1:50 Antigen retrieval : Heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH 6.0)](https://www.genetex.com/upload/website/prouct_img/normal/GTX30208/GTX30208_540_IHC-P_w_23060722_637.webp "IHC-P analysis of human brain tissue using GTX30208 Neurofibromin antibody [McNFn27a]. Dilution : 1:50 Antigen retrieval : Heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH 6.0)")
WB analysis of schwann cells from embryonic knockout mice, adult human nerves, and neonatal rat nerves using GTX30208 Neurofibromin antibody [McNFn27a].
Neurofibromin antibody [McNFn27a]
GTX30208
ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityGuinea Pig, Human, Mouse, Rat
TargetNF1
Overview
- SupplierGeneTex
- Product NameNeurofibromin antibody [McNFn27a] - KO/KD Validated
- Delivery Days Customer9
- Antibody SpecificityThis is specific for full-length or truncated forms of neurofibromin.
- Application Supplier NoteWB: 2 - 5 microg/ml. IHC-P: 1:20 - 1:50. IP: 1:10 - 1:500. ELISA: 1:100 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMcNFn27a
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4763
- Target nameNF1
- Target descriptionneurofibromin 1
- Target synonymsneurofibromatosis 1; neurofibromatosis-related protein NF-1; neurofibromin; NFNS; truncated neurofibromin 1; VRNF; WSS
- HostMouse
- IsotypeIgG1
- Protein IDP21359
- Protein NameNeurofibromin
- Scientific DescriptionThis gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq]
- ReactivityGuinea Pig, Human, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203