ProductsBack/Neurofibromin antibody [McNFn27a]

WB analysis of schwann cells from embryonic knockout mice, adult human nerves, and neonatal rat nerves using GTX30208 Neurofibromin antibody [McNFn27a].

Neurofibromin antibody [McNFn27a]

GTX30208

ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

DownloadDatasheet

Product group Antibodies

TargetNF1

Overview

Supplier
GeneTex
Product Name
Neurofibromin antibody [McNFn27a] - KO/KD Validated
Delivery Days Customer
9
Application Supplier Note
WB: 2 - 5 microg/ml. IHC-P: 1:20 - 1:50. IP: 1:10 - 1:500. ELISA: 1:100 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
McNFn27a
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID4763
Target name
NF1
Target description
neurofibromin 1
Target synonyms
neurofibromatosis 1; neurofibromatosis-related protein NF-1; neurofibromin; NFNS; truncated neurofibromin 1; VRNF; WSS
Host
Mouse
Isotype
IgG1
Protein IDP21359
Protein Name
Neurofibromin
Scientific Description
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Neurofibromin antibody [McNFn27a]

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