IHC-P analysis of adult human dorsal root ganglia tissue using GTX30209 Neurofibromin antibody [McNFn27b].
IHC-P analysis of adult human dorsal root ganglia tissue using GTX30209 Neurofibromin antibody [McNFn27b].
Neurofibromin antibody [McNFn27b]
GTX30209
ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityGuinea Pig, Human, Mouse, Rat
TargetNF1
Overview
- SupplierGeneTex
- Product NameNeurofibromin antibody [McNFn27b]
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 10 - 20 microg/ml. IP: 1:10 - 1:500. ELISA: 1:100 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMcNFn27b
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID4763
- Target nameNF1
- Target descriptionneurofibromin 1
- Target synonymsneurofibromatosis 1; neurofibromatosis-related protein NF-1; neurofibromin; NFNS; truncated neurofibromin 1; VRNF; WSS
- HostMouse
- IsotypeIgG1
- Protein IDP21359
- Protein NameNeurofibromin
- Scientific DescriptionThis gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq]
- ReactivityGuinea Pig, Human, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment. Wang Q et al., 2017 Jul 10, Cancer CellRead more