Neurogranin antibody, Internal

GeneTex

Neurogranin antibody, Internal

9

WB: 0.1-0.3microg/ml. IHC-P: 5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

NRGN

neurogranin

RC3, hng, neurogranin, calmodulin-binding protein, neurogranin (protein kinase C substrate, RC3), protein kinase C substrate

Goat

IgG

Neurogranin

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203