
WB analysis of HeLa cells untreated or treated with TNF-α lysates using GTX78998 NFkB p105 (phospho Ser907) antibody.
NFkB p105 (phospho Ser907) antibody
GTX78998
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetNFKB1
Overview
- SupplierGeneTex
- Product NameNFkB p105 (phospho Ser907) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. IHC-P: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4790
- Target nameNFKB1
- Target descriptionnuclear factor kappa B subunit 1
- Target synonymsCVID12, EBP-1, KBF1, NF-kB, NF-kB1, NF-kappa-B1, NF-kappaB, NF-kappabeta, NFKB-p105, NFKB-p50, NFkappaB, nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1, nuclear factor NF-kappa-B p50 subunit, nuclear factor kappa-B DNA binding subunit, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- HostRabbit
- IsotypeIgG
- Protein IDP19838
- Protein NameNuclear factor NF-kappa-B p105 subunit
- Scientific DescriptionThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed. [provided by RefSeq, Feb 2016]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203



![WB analysis of K562 (1), Jurkat (2), A431 (3), HeLa (4), THP-1 (5) and MCF-7 (6) cell lysate using GTX60455 NFkB p105/p50 antibody [5D10].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60455/GTX60455_20170912_WB_w_23061123_593.webp)
![ELISA analysis of antigen using GTX60465 NFkB p105/p50 antibody [5D10D11].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng](https://www.genetex.com/upload/website/prouct_img/normal/GTX60465/GTX60465_20170912_ELISA_w_23061123_183.webp)
![Wild-type (WT) and NFKB1 knockout (KO) HeLa cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with NFkB p105 antibody [HL1784] (GTX637436) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.](https://www.genetex.com/upload/website/prouct_img/normal/GTX637436/GTX637436_T-44802_20221014_WB_KO_watermark_22101717_495.webp)


