NGFR (Nerve Growth Factor Receptor)(NGFR5), 1mg/mL [26628-22-8]

Biotium

NGFR (Nerve Growth Factor Receptor)(NGFR5), 1mg/mL [26628-22-8]

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

26628-22-8

Research Use Only

Monoclonal

NGFR5

1 mg/ml

NGFR

nerve growth factor receptor

CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR, tumor necrosis factor receptor superfamily member 16, NGF receptor, TNFR superfamily, member 16, low affinity neurotrophin receptor p75NTR, low-affinity nerve growth factor receptor, low-affinity nerve growth factor receptor p75NGFR, low-affinity nerve growth factor receptor p75NGR, p75 ICD

Mouse

IgG1

Tumor necrosis factor receptor superfamily member 16

This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Feline, Ferret, Human, Monkey, Mouse, Primate, Rabbit

-20°C

41116161