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NLRP3/AIM2-IN-3

M45372
AbMole BioScience
CAS Number1787787-60-3
Product group Chemicals
Molecular Weight266.29
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    NLRP3/AIM2-IN-3
  • Delivery Days Customer
    9
  • CAS Number
    1787787-60-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C16H14N2O2
  • Molecular Weight
    266.29
  • Scientific Description
    NLRP3/AIM2-IN-3 is a potent inhibitor that interferes with the interaction of NLRP3 or AIM2 with the bridging protein ASC and inhibits ASC oligomerization, and has different species-specific effects on NLRP3 and AIM2 inflammasome-dependent pyroptosis. In addition, NLRP3/AIM2-IN-3 inhibited LPS/nigericin-stimulated cell pyroptosis in THP-1 macrophages with an IC50 of 0.077 ± 0.008 uM.
  • UNSPSC
    12352200

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NLRP3/AIM2-IN-3 [1787787-60-3]
Product group Chemicals
References
TargetMol Chemicals
NLRP3/AIM2-IN-3 [1787787-60-3]T60442
CAS Number1787787-60-3
Estimated Purity97.16%
Molecular Weight266.29
  • SizePrice