![IHC-P analysis of human Placenta tissue using GTX83325 nm23-H1 antibody [4B2]. IHC-P analysis of human Placenta tissue using GTX83325 nm23-H1 antibody [4B2].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83325/GTX83325_20170912_IHC-P_w_23061322_231.webp)
IHC-P analysis of human Placenta tissue using GTX83325 nm23-H1 antibody [4B2].
nm23-H1 antibody [4B2]
GTX83325
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetNME1
Overview
- SupplierGeneTex
- Product Namenm23-H1 antibody [4B2]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. FCM: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID4B2
- ConjugateUnconjugated
- Gene ID4830
- Target nameNME1
- Target descriptionNME/NM23 nucleoside diphosphate kinase 1
- Target synonymsAWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1, nucleoside diphosphate kinase A, NDP kinase A, epididymis secretory sperm binding protein, granzyme A-activated DNase, metastasis inhibition factor nm23, non-metastatic cells 1, protein (NM23A) expressed in, tumor metastatic process-associated protein
- HostMouse
- IsotypeIgG1
- Protein IDP15531
- Protein NameNucleoside diphosphate kinase A
- Scientific DescriptionThis gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by this gene) and B (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC41116161
References
- Negative Effect of Reduced NME1 Expression on Recurrence-Free Survival in Early Stage Non-Small Cell Lung Cancer. Kim D et al., 2020 Sep 23, J Clin MedRead this paper
![ICC/IF analysis of HeLa cells using GTX83325 nm23-H1 antibody [4B2]. Green : nm23-H1 Blue: DRAQ5 fluorescent DNA dye Red: Actin filaments ICC/IF analysis of HeLa cells using GTX83325 nm23-H1 antibody [4B2]. Green : nm23-H1 Blue: DRAQ5 fluorescent DNA dye Red: Actin filaments](https://www.genetex.com/upload/website/prouct_img/normal/GTX83325/GTX83325_20170912_ICCIF_w_23061322_398.webp)
![FACS analysis of Jurkat cells using GTX83325 nm23-H1 antibody [4B2]. Green : nm23-H1 Purple : negative control FACS analysis of Jurkat cells using GTX83325 nm23-H1 antibody [4B2]. Green : nm23-H1 Purple : negative control](https://www.genetex.com/upload/website/prouct_img/normal/GTX83325/GTX83325_20170912_FACS_w_23061322_853.webp)
![WB analysis of nm23-H1(AA: 27-177)-hIgGFc transfected HEK293 cell lysate using GTX83325 nm23-H1 antibody [4B2]. WB analysis of nm23-H1(AA: 27-177)-hIgGFc transfected HEK293 cell lysate using GTX83325 nm23-H1 antibody [4B2].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83325/GTX83325_20170912_WB_w_23061322_866.webp)






![nm23-H1 antibody [C1C3] detects nm23-H1 protein at cytosol on human endometrial carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human endometrial carcinoma. nm23-H1 antibody [C1C3] (GTX108325) dilution: 1:500.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min](https://www.genetex.com/upload/website/prouct_img/normal/GTX108325/GTX108325_39834_IHC_w_23060120_852.webp)
