WB analysis of human fibroblast cell lysate using GTX30687 NPC1 antibody. Loading : 20microg
WB analysis of human fibroblast cell lysate using GTX30687 NPC1 antibody. Loading : 20microg
NPC1 antibody
GTX30687
ApplicationsElectron Microscopy, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHamster, Human, Mouse, Porcine, Primate, Rat
TargetNPC1
Overview
- SupplierGeneTex
- Product NameNPC1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000 - 1:3000. ICC/IF: 1:250. IHC-P: 5 - 10 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsElectron Microscopy, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4864
- Target nameNPC1
- Target descriptionNPC intracellular cholesterol transporter 1
- Target synonymsNiemann-Pick C1 protein; NPC; NPC intracellular cholesterol transporter 1; POGZ; SLC65A1; truncated Niemann-Pick C1
- HostRabbit
- IsotypeIgG
- Protein IDO15118
- Protein NameNPC intracellular cholesterol transporter 1
- Scientific DescriptionThis gene was identified as the gene that when mutated, results in Niemann-Pick C disease. The encoded protein is a putative integral membrane protein that contains motifs consistent with a role in intracellular transport of cholesterol to post-lysosomal destinations. [provided by RefSeq]
- ReactivityHamster, Human, Mouse, Porcine, Primate, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function. Frolov A et al., 2001 Dec 7, J Biol ChemRead more
- Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis. Millard EE et al., 2000 Dec 8, J Biol ChemRead more