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WB analysis of human fibroblast cell lysate using GTX30687 NPC1 antibody. Loading : 20microg
WB analysis of human fibroblast cell lysate using GTX30687 NPC1 antibody. Loading : 20microg
WB analysis of human fibroblast cell lysate using GTX30687 NPC1 antibody. Loading : 20microg

NPC1 antibody

GTX30687
GeneTex
ApplicationsElectron Microscopy, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetNPC1
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Overview

  • Supplier
    GeneTex
  • Product Name
    NPC1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000 - 1:3000. ICC/IF: 1:250. IHC-P: 5 - 10 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Electron Microscopy, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4864
  • Target name
    NPC1
  • Target description
    NPC intracellular cholesterol transporter 1
  • Target synonyms
    Niemann-Pick C1 protein; NPC; NPC intracellular cholesterol transporter 1; POGZ; SLC65A1; truncated Niemann-Pick C1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO15118
  • Protein Name
    NPC intracellular cholesterol transporter 1
  • Scientific Description
    This gene was identified as the gene that when mutated, results in Niemann-Pick C disease. The encoded protein is a putative integral membrane protein that contains motifs consistent with a role in intracellular transport of cholesterol to post-lysosomal destinations. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function. Frolov A et al., 2001 Dec 7, J Biol Chem
    Read more
  • Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis. Millard EE et al., 2000 Dec 8, J Biol Chem
    Read more

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