Bio-Connect

NQO1 antibody [C2C3], C-term

GTX100235
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetNQO1
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    NQO1 antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.61 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1728
  • Target name
    NQO1
  • Target description
    NAD(P)H quinone dehydrogenase 1
  • Target synonyms
    DHQU, DIA4, DTD, NMOR1, NMORI, QR1, NAD(P)H dehydrogenase [quinone] 1, DT-diaphorase, NAD(P)H dehydrogenase, quinone 1, NAD(P)H-quinone oxidoreductase, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, azoreductase, diaphorase (NADH/NADPH) (cytochrome b-5 reductase), diaphorase-4, dioxin-inducible 1, menadione reductase, phylloquinone reductase, quinone reductase 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP15559
  • Protein Name
    NAD(P)H dehydrogenase [quinone] 1
  • Scientific Description
    This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This proteins enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimers disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Lu YU, Miyamoto T, Takeuchi H, et al. PPARα activator irbesartan suppresses the proliferation of endometrial carcinoma cells via SREBP1 and ARID1A. Oncol Res. 2023,31(3):239-253. doi: 10.32604/or.2023.026067
    Read this paper
  • Lai W, Li D, Wang Q, et al. Bacterial Magnetosomes Release Iron Ions and Induce Regulation of Iron Homeostasis in Endothelial Cells. Nanomaterials (Basel). 2022,12(22). doi: 10.3390/nano12223995
    Read this paper
  • Ren J, Zhang S, Wang X, et al. MEF2C ameliorates learning, memory, and molecular pathological changes in Alzheimer’s disease in vivo and in vitro. Acta Biochim Biophys Sin (Shanghai). 2022,54(1):77-90. doi: 10.3724/abbs.2021012
    Read this paper
  • Chao TY, Hsieh CC, Kuo YH, et al. Bracteanolide A abrogates oxidative stress-induced cellular damage and protects against hepatic ischemia and reperfusion injury in rats. Food Sci Nutr. 2021,9(9):4758-4769. doi: 10.1002/fsn3.2374
    Read this paper
  • Hori Y, Tsutsumi R, Nasu K, et al. Aromatic-Turmerone Analogs Protect Dopaminergic Neurons in Midbrain Slice Cultures through Their Neuroprotective Activities. Cells. 2021,10(5). doi: 10.3390/cells10051090
    Read this paper
  • Kuang Y, Zhang Y, Xiao Z, et al. Protective effect of dimethyl fumarate on oxidative damage and signaling in cardiomyocytes. Mol Med Rep. 2020,22(4):2783-2790. doi: 10.3892/mmr.2020.11342
    Read this paper
  • Lin DS, Ho CS, Huang YW, et al. Impairment of Proteasome and Autophagy Underlying the Pathogenesis of Leukodystrophy. Cells. 2020,9(5). doi: 10.3390/cells9051124
    Read this paper
  • Huang SY, Chang SF, Chau SF, et al. The Protective Effect of Hispidin against Hydrogen Peroxide-Induced Oxidative Stress in ARPE-19 Cells via Nrf2 Signaling Pathway. Biomolecules. 2019,9(8). doi: 10.3390/biom9080380
    Read this paper
  • Wu CT, Deng JS, Huang WC, et al. Salvianolic Acid C against Acetaminophen-Induced Acute Liver Injury by Attenuating Inflammation, Oxidative Stress, and Apoptosis through Inhibition of the Keap1/Nrf2/HO-1 Signaling. Oxid Med Cell Longev. 2019,2019:9056845. doi: 10.1155/2019/9056845
    Read this paper
  • Cai J, Pires KM, Ferhat M, et al. Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk. Cell Rep. 2018,25(7):1708-1717.e5. doi: 10.1016/j.celrep.2018.10.040
    Read this paper