Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA016052ESR1HU at dilution of 1:100
NR2C2 Antibody
CSB-PA016052ESR1HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetNR2C2
Overview
- SupplierCusabio
- Product NameNR2C2 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7182
- Target nameNR2C2
- Target descriptionnuclear receptor subfamily 2 group C member 2
- Target synonymsNuclear hormone receptor TR4; nuclear receptor subfamily 2 group C member 2; orphan nuclear receptor TAK1; orphan nuclear receptor TR4; orphan receptor TR4; TAK1; testicular nuclear receptor 4; TR4
- HostRabbit
- IsotypeIgG
- Protein IDP49116
- Protein NameNuclear receptor subfamily 2 group C member 2
- Scientific DescriptionOrphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5\\\-AGGTCA-3\\\ half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior (By similarity). Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203