NRF1 antibody
GTX103179
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetNRF1
Overview
- SupplierGeneTex
- Product NameNRF1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.69 mg/ml
- ConjugateUnconjugated
- Gene ID4899
- Target nameNRF1
- Target descriptionnuclear respiratory factor 1
- Target synonymsalpha palindromic-binding protein; ALPHA-PAL; nuclear respiratory factor 1
- HostRabbit
- IsotypeIgG
- Protein IDQ16656
- Protein NameNuclear respiratory factor 1
- Scientific DescriptionThis gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for nuclear factor (erythroid-derived 2)-like 1 which has an official symbol of NFE2L1. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Timely expression of PGAM5 and its cleavage control mitochondrial homeostasis during neurite re-growth after traumatic brain injury.Read more
- Resistance Training Diminishes Mitochondrial Adaptations to Subsequent Endurance Training.Read more
- Effects of aging and long-term physical activity on mitochondrial physiology and redox state of the cortex and cerebellum of female rats.Read more
- mito-TEMPO Attenuates Oxidative Stress and Mitochondrial Dysfunction in Noise-Induced Hearing Loss via Maintaining TFAM-mtDNA Interaction and Mitochondrial Biogenesis. Chen JW et al., 2022, Front Cell NeurosciRead more
- Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults. Mesquita PHC et al., 2020 Aug, Physiol RepRead more
- The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression. Ma B et al., 2019 Mar 4, Nat CommunRead more
- 1,25-Dihydroxyvitamin D3 modulates the effects of sublethal BPA on mitochondrial function via activating PI3K-Akt pathway and 17beta-estradiol secretion in rat granulosa cells. Lee CT et al., 2019 Jan, J Steroid Biochem Mol BiolRead more
- A mitohormetic response to pro-oxidant exposure in the house mouse. Zhang Y et al., 2018 Jan 1, Am J Physiol Regul Integr Comp PhysiolRead more
- Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia. Chen YH et al., 2016, PLoS OneRead more
- Rosiglitazone activation of PPARgamma-dependent signaling is neuroprotective in mutant huntingtin expressing cells. Chiang MC et al., 2015 Nov 1, Exp Cell ResRead more