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ProductsBack/NRF2 antibody [N2C2], Internal

NRF2 antibody [N2C2], Internal

GTX103322
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityAvian, Human, Mouse, Plant, Reptile, Rat, Zebra Fish
TargetNFE2L2
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Overview

  • Supplier
    GeneTex
  • Product Name
    NRF2 antibody [N2C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.31 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4780
  • Target name
    NFE2L2
  • Target description
    nuclear factor, erythroid 2 like 2
  • Target synonyms
    HEBP1; IMDDHH; NRF2; Nrf-2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ16236
  • Protein Name
    Nuclear factor erythroid 2-related factor 2
  • Scientific Description
    NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995 [PubMed 7868116]).[supplied by OMIM]
  • Reactivity
    Avian, Human, Mouse, Plant, Reptile, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Prinsepiae Nux Extract Activates NRF2 Activity and Protects UVB-Induced Damage in Keratinocyte. Wang SH et al., 2022 Sep 5, Antioxidants (Basel)
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  • Gut Microbiota Mediates the Susceptibility of Mice to Sepsis-Associated Encephalopathy by Butyric Acid. Zhang H et al., 2022, J Inflamm Res
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  • NOX4 regulates TGFbeta-induced proliferation and self-renewal in glioblastoma stem cells. Garcia-Gomez P et al., 2022 May, Mol Oncol
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  • Xanthohumol Protects the Rat Myocardium against Ischemia/Reperfusion Injury-Induced Ferroptosis. Lin JH et al., 2022, Oxid Med Cell Longev
    Read more
  • Activation of alpha7 Nicotinic Acetylcholine Receptor by its Selective Agonist Improved Learning and Memory of Amyloid Precursor Protein/Presenilin 1 (APP/PS1) Mice via the Nrf2/HO-1 Pathway. Cao K et al., 2022 Jan 4, Med Sci Monit
    Read more
  • Protective Effects of Dexmedetomidine on Sepsis-Induced Vascular Leakage by Alleviating Ferroptosis via Regulating Metabolic Reprogramming. She H et al., 2021, J Inflamm Res
    Read more
  • Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis. Liu Y et al., 2021, Front Pharmacol
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  • Gossypol Acetic Acid Attenuates Cardiac Ischemia/Reperfusion Injury in Rats via an Antiferroptotic Mechanism. Lin JH et al., 2021 Nov 10, Biomolecules
    Read more
  • Protective effect of sargahydroquinoic acid against Abeta25-35-evoked damage via PI3K/Akt mediated Nrf2 antioxidant defense system. Yoon JH et al., 2021 Dec, Biomed Pharmacother
    Read more
  • Pre- and Early Post-treatment With Arthrospira platensis (Spirulina) Extract Impedes Lipopolysaccharide-triggered Neuroinflammation in Microglia. Piovan A et al., 2021, Front Pharmacol
    Read more