Bio-Connect

NRF2 antibody [N2C2], Internal

GTX103322
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityAvian, Human, Mouse, Plant, Reptile, Rat, Zebra Fish
TargetNFE2L2
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Overview

  • Supplier
    GeneTex
  • Product Name
    NRF2 antibody [N2C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.21 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4780
  • Target name
    NFE2L2
  • Target description
    nuclear factor, erythroid 2 like 2
  • Target synonyms
    HEBP1; IMDDHH; NRF2; Nrf-2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ16236
  • Protein Name
    Nuclear factor erythroid 2-related factor 2
  • Scientific Description
    NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995 [PubMed 7868116]).[supplied by OMIM]
  • Reactivity
    Avian, Human, Mouse, Plant, Reptile, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Allyl methyl disulfide (AMDS) prevents N,N-dimethyl formamide-induced liver damage by suppressing oxidative stress and NLRP3 inflammasome activation.
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  • Anti-inflammatory effects of cold atmospheric plasma irradiation on the THP-1 human acute monocytic leukemia cell line.
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  • Antioxidant and anti-inflammatory effects of allicin in the kidney of an experimental model of metabolic syndrome.
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  • Zinc Oxide Nanoparticles (ZnO-NPs) Induce Cytotoxicity in the Zebrafish Olfactory Organs via Activating Oxidative Stress and Apoptosis at the Ultrastructure and Genetic Levels.
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  • Allicin, an Emerging Treatment for Pulmonary Arterial Hypertension: An Experimental Study.
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  • The Potential Effects of Quercetin-Loaded Nanoliposomes on Amoxicillin/Clavulanate-Induced Hepatic Damage: Targeting the SIRT1/Nrf2/NF-kappaB Signaling Pathway and Microbiota Modulation.
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  • Sulforaphane Inhibits Foam Cell Formation and Atherosclerosis via Mechanisms Involving the Modulation of Macrophage Cholesterol Transport and the Related Phenotype.
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  • Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10.
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  • Sivelestat sodium attenuates acute lung injury by inhibiting JNK/NF-kappaB and activating Nrf2/HO-1 signaling pathways.
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