WB analysis of 293 cell lysate using GTX85185 NSE2 antibody. Working concentration : (A) 0.5 and (B) 1 microg/ml
WB analysis of 293 cell lysate using GTX85185 NSE2 antibody. Working concentration : (A) 0.5 and (B) 1 microg/ml
NSE2 antibody
GTX85185
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetNSMCE2
Overview
- SupplierGeneTex
- Product NameNSE2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 0.5 - 1 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID286053
- Target nameNSMCE2
- Target descriptionNSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase
- Target synonymsC8orf36; E3 SUMO-protein ligase NSE2; E3 SUMO-protein transferase NSE2; methyl methanesulfonate sensitivity gene 21; MMS21; non-SMC element 2, MMS21 homolog; non-structural maintenance of chromosomes element 2 homolog; NSE2; NSMCE2/PVT1 fusion; PVT1/NSMCE2 fusion; zinc finger, MIZ-type containing 7; ZMIZ7
- HostRabbit
- IsotypeIgG
- Protein IDQ96MF7
- Protein NameE3 SUMO-protein ligase NSE2
- Scientific DescriptionMMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203