![IHC-P analysis of human liver cancer tissue using GTX17430 NTCP antibody. IHC-P analysis of human liver cancer tissue using GTX17430 NTCP antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX17430/GTX17430_20190815_IHC-P_w_23060620_364.webp)
IHC-P analysis of human liver cancer tissue using GTX17430 NTCP antibody.
NTCP antibody
![Research Use Only](static/images/certificates/ruo.jpg)
GTX17430
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSLC10A1
Overview
- SupplierGeneTex
- Product NameNTCP antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 0.1-0.5microg/ml. IHC-P: 0.5-1microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration500 ug/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID6554
- Target nameSLC10A1
- Target descriptionsolute carrier family 10 member 1
- Target synonymscell growth-inhibiting gene 29 protein; FHCA2; growth-inhibiting protein 29; Na(+)/bile acid cotransporter; Na(+)/taurocholate transport protein; Na/taurocholate cotransporting polypeptide; NTCP; sodium/bile acid cotransporter; sodium/taurocholate cotransporter; sodium/taurocholate cotransporting polypeptide; solute carrier family 10 (sodium/bile acid cotransporter family), member 1; solute carrier family 10 (sodium/bile acid cotransporter), member 1
- HostRabbit
- IsotypeIgG
- Protein IDQ14973
- Protein NameSodium/bile acid cotransporter
- Scientific DescriptionThe protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis. [provided by RefSeq, Oct 2011]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Up-regulation of miR-let7a-5p Leads to Decreased Expression of ABCC2 in Obstructive Cholestasis. Balasubramaniyan N et al., 2019 Dec, Hepatol CommunRead more