Nutlin-3 [548472-68-0]
T2158
CAS Number548472-68-0
Product group Chemicals
Estimated Purity99.89%
Molecular Weight581.49
Overview
- SupplierTargetMol Chemicals
- Product NameNutlin-3 [548472-68-0]
- Delivery Days Customer4
- CAS Number548472-68-0
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameNutlin-3
- Estimated Purity99.89%
- Molecular FormulaC30H30Cl2N4O4
- Molecular Weight581.49
- Scientific DescriptionNutlin-3 is an MDM2 antagonist that inhibits MDM2-p53 interaction (Ki=90 nM) and activates p53. Nutlin-3 binds preferentially to the p53-binding pocket of MDM2, leading to stabilization of p53 and activation of the p53 pathway. Nutlin-3 has antitumor activity.
- Shelf life instruction3 years
- SMILESCOc1ccc(C2=NC(C(N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1
- Storage Instruction-20°C
- UNSPSC12352200
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