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ProductsBack/NVP-2 [1263373-43-8]

NVP-2 [1263373-43-8]

Research Use Only
HY-12214A
MedChem Express
CAS Number1263373-43-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.60
Molecular Weight513.07
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Overview

  • Supplier
    MedChem Express
  • Product Name
    NVP-2 [1263373-43-8]
  • Delivery Days Customer
    10
  • CAS Number
    1263373-43-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.60
  • Molecular Formula
    C27H37ClN6O2
  • Molecular Weight
    513.07
  • Scientific Description
    NVP-2 is a potent and selective ATP-competitive cyclin dependent kinase 9 (CDK9) probe, inhibits CDK9/CycT activity with an IC50 of 0.514 nM. NVP-2 displays inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases with IC50 values of 0.584 microM, 0.706 microM, and 0.605 microM, respectively. NVP-2 induces cell apoptosis.[1]
  • SMILES
    ClC1=CN=C(N[C@H]2CC[C@H](N[C@H](C)COC)CC2)C=C1C3=CC=CC(NCC4(C#N)CCOCC4)=N3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200