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NVP-2

M10705
AbMole BioScience
CAS Number1263373-43-8
Product group Chemicals
Molecular Weight513.07
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    NVP-2
  • Delivery Days Customer
    9
  • CAS Number
    1263373-43-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C27H37ClN6O2
  • Molecular Weight
    513.07
  • Scientific Description
    NVP-2 is an effective and selective ATP competitive cyclin-dependent kinase 9 (CDK9) probe that inhibits CDK9/CycT activity.IC50 The value is 0.514 nM. NVP-2 has inhibitory effects on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases, which IC50 The values are 0.584 uM, 0.706 uM, and 0.605 uM, respectively. NVP-2 induces apoptosis.
  • SMILES
    COCC(C)NC1CCC(CC1)NC2=CC(=C(Cl)C=N2)C3=NC(=CC=C3)NCC4(CCOCC4)C#N
  • UNSPSC
    12352200