NVP-2 [1263373-43-8]

TargetMol Chemicals

NVP-2 [1263373-43-8]

4

1263373-43-8

Chemical

Research Use Only

NVP-2

99.76%

C27H37ClN6O2

513.07

NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50: 0.514 nM). NVP-2 shows inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases (IC50: 0.584 microM, 0.706 microM, and 0.605 microM, respectively).

3 years

COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1

-20°C

12352200