
Human plasma (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with OPG antibody (GTX127948) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
OPG antibody
GTX127948
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTNFRSF11B
Overview
- SupplierGeneTex
- Product NameOPG antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.48 mg/ml
- ConjugateUnconjugated
- Gene ID4982
- Target nameTNFRSF11B
- Target descriptionTNF receptor superfamily member 11b
- Target synonymsOCIF, OPG, PDB5, TR1, tumor necrosis factor receptor superfamily member 11B, osteoclastogenesis inhibitory factor, osteoprotegerin, tumor necrosis factor receptor superfamily, member 11b
- HostRabbit
- IsotypeIgG
- Protein IDO00300
- Protein NameTumor necrosis factor receptor superfamily member 11B
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- He HQ, Qu YQ, Kwan Law BY, et al. AGEs-Induced Calcification and Apoptosis in Human Vascular Smooth Muscle Cells Is Reversed by Inhibition of Autophagy. Front Pharmacol. 2021,12:692431. doi: 10.3389/fphar.2021.692431Read this paper
- Chang MC, Chen YJ, Lian YC, et al. Butyrate Stimulates Histone H3 Acetylation, 8-Isoprostane Production, RANKL Expression, and Regulated Osteoprotegerin Expression/Secretion in MG-63 Osteoblastic Cells. Int J Mol Sci. 2018,19(12). doi: 10.3390/ijms19124071Read this paper







![WB analysis of HEK293 (1) and OPG (AA: 22-401)-hIgGFc transfected HEK293 (2) cell lysate using GTX80404 OPG antibody [5A11].](https://www.genetex.com/upload/website/prouct_img/normal/GTX80404/GTX80404_20170912_WB_w_23061322_190.webp)
![WB analysis of HEK293 (1) and OPG (AA: 22-401)-hIgGFc transfected HEK293 (2) cell lysate using GTX82749 OPG antibody [5G2].](https://www.genetex.com/upload/website/prouct_img/normal/GTX82749/GTX82749_20170912_WB_w_23061322_278.webp)

