WB analysis of Jurkat cell lysate using GTX85443 ORAI2 antibody. Working concentration : (A) 1, (B) 2, and (C) 4 microg/ml
WB analysis of Jurkat cell lysate using GTX85443 ORAI2 antibody. Working concentration : (A) 1, (B) 2, and (C) 4 microg/ml
ORAI2 antibody
GTX85443
Overview
- SupplierGeneTex
- Product NameORAI2 antibody
- Delivery Days Customer9
- Antibody SpecificityAt least two isoforms of ORAI2 are known to exist; this antibody will detect both isoforms. ORAI antibody is predicted not to cross-react with ORAI1 or ORAI3.
- Application Supplier NoteWB: 1 - 4 microg/mL. ICC/IF: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Concentration1 mg/ml
- FormulationLiquid
- Gene ID80228
- Target nameORAI2
- Target descriptionORAI calcium release-activated calcium modulator 2
- Target synonymsC7orf19; CAP-binding protein complex interacting protein 2; CBCIP2; H_NH0514P08.8; MEM142B; protein orai-2; putative protein ORAI2-2; TMEM142B; transmembrane protein 142B
- Protein IDQ96SN7
- Protein NameProtein orai-2
- Scientific DescriptionAntigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI3.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203