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Osteocalcin antibody

GTX132902
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetBGLAP
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Overview

  • Supplier
    GeneTex
  • Product Name
    Osteocalcin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.32 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID632
  • Target name
    BGLAP
  • Target description
    bone gamma-carboxyglutamate protein
  • Target synonyms
    BGP; bone gamma-carboxyglutamate (gla) protein (osteocalcin); gamma-carboxyglutamic acid-containing protein; OC; OCN; osteocalcin
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP02818
  • Protein Name
    Osteocalcin
  • Scientific Description
    This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Effects of transforming growth factor-beta1 on plasminogen activation in stem cells from the apical papilla: role of activating receptor-like kinase 5/Smad2 and mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) signalling. Chang MC et al., 2020 May, Int Endod J
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