Osteocalcin antibody [8H12F9H10]

GeneTex

Osteocalcin antibody [8H12F9H10]

9

This antibody reacts with osteocalcin fragments corresponding to amino acids 1-19, 7-19 and 15-31 of the native molecule. It does not recognize fragments representing amino acids 20-43 or intact bovine osteocalcin.

ELISA

Research Use Only

Monoclonal

8H12F9H10

1 mg/ml

Unconjugated

BGLAP

bone gamma-carboxyglutamate protein

BGP; bone gamma-carboxyglutamate (gla) protein (osteocalcin); gamma-carboxyglutamic acid-containing protein; OC; OCN; osteocalcin

Mouse

IgG1

Osteocalcin

This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]

Bovine, Human, Porcine, Rabbit, Rat

-20°C or -80°C,2°C to 8°C

12352203