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ProductsBack/Osteocalcin antibody

WB analysis of HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates using GTX55255 Osteocalcin antibody.

WB analysis of HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates using GTX55255 Osteocalcin antibody.

WB analysis of HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates using GTX55255 Osteocalcin antibody.

Osteocalcin antibody

GTX55255

ApplicationsWestern Blot

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetBGLAP

Overview

Supplier
GeneTex
Product Name
Osteocalcin antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID632
Target name
BGLAP
Target description
bone gamma-carboxyglutamate protein
Target synonyms
BGP, OC, OCN, osteocalcin, bone gamma-carboxyglutamate (gla) protein (osteocalcin), gamma-carboxyglutamic acid-containing protein
Host
Rabbit
Isotype
IgG
Protein IDP02818
Protein Name
Osteocalcin
Scientific Description
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Zuo X, Wei X, Ju C, et al. Protective Effect of Photobiomodulation against Hydrogen Peroxide-Induced Oxidative Damage by Promoting Autophagy through Inhibition of PI3K/AKT/mTOR Pathway in MC3T3-E1 Cells. Oxid Med Cell Longev. 2022,2022:7223353. doi: 10.1155/2022/7223353
Read this paper
Yang Y, Miao L, Chang S, et al. Exosome-Derived LncRNA TCONS_00072128 Mediated Osteogenic Differentiation and Inflammation by Caspase 8 Regulation. Front Genet. 2021,12:831420. doi: 10.3389/fgene.2021.831420
Read this paper

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