OTUD5 antibody [C1C3]

GeneTex

OTUD5 antibody [C1C3]

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

OTUD5

OTU deubiquitinase 5

deubiquinating enzyme A; deubiquitinating enzyme A; DUBA; MCAND; OTU domain containing 5; OTU domain-containing protein 5

Rabbit

IgG

OTU domain-containing protein 5

This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203