WB analysis of rat brain membrane?(1, 2) and human platelets (3, 4) lysates using GTX54796 P2Y12 antibody preincubated with or without immunogen peptide. Dilution : 1:200

P2Y12 antibody

GTX54796

ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetP2RY12

Overview

Supplier
GeneTex
Product Name
P2Y12 antibody
Delivery Days Customer
7
Applications
Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.8 mg/ml
Conjugate
Unconjugated
Gene ID64805
Target name
P2RY12
Target description
purinergic receptor P2Y12
Target synonyms
ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, SP1999, P2Y purinoceptor 12, ADP-glucose receptor, G-protein coupled receptor SP1999, Gi-coupled ADP receptor HORK3, P2Y12 platelet ADP receptor, purinergic receptor P2RY12, purinergic receptor P2Y, G-protein coupled, 12, putative G-protein coupled receptor
Host
Rabbit
Isotype
IgG
Protein IDQ9H244
Protein Name
P2Y purinoceptor 12
Scientific Description
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Jin C, Wu Y, Zhang H, et al. Spinal cord tissue engineering using human primary neural progenitor cells and astrocytes. Bioeng Transl Med. 2023,8(2):e10448. doi: 10.1002/btm2.10448
Read this paper
Siegel PM, Sander L, Fricke A, et al. P(2)Y(12) receptor blockers are anti-inflammatory drugs inhibiting both circulating monocytes and macrophages including THP-1 cells. Sci Rep. 2021,11(1):17459. doi: 10.1038/s41598-021-95710-3
Read this paper

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P2Y12 antibody

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Overview

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