IHC-P analysis of human colon carcinoma tissue using GTX34939 p57 Kip2 antibody [KP10].
IHC-P analysis of human colon carcinoma tissue using GTX34939 p57 Kip2 antibody [KP10].
p57 Kip2 antibody [KP10]
GTX34939
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetCDKN1C
Overview
- SupplierGeneTex
- Product Namep57 Kip2 antibody [KP10]
- Delivery Days Customer9
- Antibody SpecificityRecognizes a protein of 57kDa, identified as p57Kip2. It shows no cross-reaction with p27Kip1.
- Application Supplier NoteIHC-P: 1-2microg/ml for 30 min at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDKP10
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID1028
- Target nameCDKN1C
- Target descriptioncyclin dependent kinase inhibitor 1C
- Target synonymsBWCR; BWS; cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor p57; KIP2; p57; p57Kip2; WBS
- HostMouse
- IsotypeIgG2b
- Protein IDP49918
- Protein NameCyclin-dependent kinase inhibitor 1C
- Scientific DescriptionThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203