PARP antibody [A6.4.12]
GTX75098
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityDrosophila, Hamster, Human, Mouse, Rat, Xenopus
TargetPARP1
Overview
- SupplierGeneTex
- Product NamePARP antibody [A6.4.12]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/1,000-1/5,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDA6.4.12
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID142
- Target namePARP1
- Target descriptionpoly(ADP-ribose) polymerase 1
- Target synonymsADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); ADPRT; ADPRT 1; ADPRT1; ARTD1; DNA ADP-ribosyltransferase PARP1; NAD(+) ADP-ribosyltransferase 1; pADPRT-1; PARP; PARP-1; poly (ADP-ribose) polymerase family, member 1; poly [ADP-ribose] polymerase 1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; poly[ADP-ribose] synthase 1; PPOL; protein poly-ADP-ribosyltransferase PARP1
- HostMouse
- IsotypeIgG1
- Protein IDP09874
- Protein NamePoly [ADP-ribose] polymerase 1
- Scientific DescriptionThis gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
- ReactivityDrosophila, Hamster, Human, Mouse, Rat, Xenopus
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Quantitation of DNA double-strand break resection intermediates in human cells. Zhou Y et al., 2014 Feb, Nucleic Acids ResRead more
- DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM). Zhou Y et al., 2013 Dec 27, J Biol ChemRead more
- The protective effects of spirulina in cyclophosphamide induced nephrotoxicity and urotoxicity in rats. Sinanoglu O et al., 2012 Dec, UrologyRead more
- Quercetin 3-O-methyl ether protects FL83B cells from copper induced oxidative stress through the PI3K/Akt and MAPK/Erk pathway. Tseng HL et al., 2012 Oct 1, Toxicol Appl PharmacolRead more