PARP antibody

Name: PARP antibody
SKU: GTX100573_G10
Availability: BackOrder

GTX100573

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

DownloadDatasheet

Product group Antibodies

TargetPARP1

Overview

Supplier
GeneTex
Product Name
PARP antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.3 mg/ml
Conjugate
Unconjugated
Gene ID142
Target name
PARP1
Target description
poly(ADP-ribose) polymerase 1
Target synonyms
ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); ADPRT; ADPRT 1; ADPRT1; ARTD1; DNA ADP-ribosyltransferase PARP1; NAD(+) ADP-ribosyltransferase 1; pADPRT-1; PARP; PARP-1; poly (ADP-ribose) polymerase family, member 1; poly [ADP-ribose] polymerase 1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; poly[ADP-ribose] synthase 1; PPOL; protein poly-ADP-ribosyltransferase PARP1
Host
Rabbit
Isotype
IgG
Protein IDP09874
Protein Name
Poly [ADP-ribose] polymerase 1
Scientific Description
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

The triglyceride-glucose index predicts 1-year major adverse cardiovascular events in end-stage renal disease patients with coronary artery disease.
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Rosmarinic acid treatment protects against lethal H1N1 virus-mediated inflammation and lung injury by promoting activation of the h-PGDS-PGD(2)-HO-1 signal axis.
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YAP nuclear translocation induced by HIF-1alpha prevents DNA damage under hypoxic conditions.
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Cyclovirobuxine D pretreatment ameliorates septic heart injury through mitigation of ferroptosis.
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alpha-Viniferin-Induced Apoptosis through Downregulation of SIRT1 in Non-Small Cell Lung Cancer Cells.
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Diet-induced obesity augments ischemic myopathy and functional decline in a murine model of peripheral artery disease.
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Transcriptional upregulation of MAPK15 by NF-kappaB signaling boosts the efficacy of combination therapy with cisplatin and TNF-alpha.
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Chronic Hypergravity Induces a Modification of Histone H3 Lysine 27 Trimethylation at TCRbeta Locus in Murine Thymocytes.
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A novel NRF2/ARE inhibitor gossypol induces cytotoxicity and sensitizes chemotherapy responses in chemo-refractory cancer cells.
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2,3,5,4-Tetrahydroxystilbene-2-O-beta-glucoside Attenuates Reactive Oxygen Species-Dependent Inflammation and Apoptosis in Porphyromonas gingivalis-Infected Brain Endothelial Cells. Charoensaensuk V et al., 2022 Apr 8, Antioxidants (Basel)
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PARP antibody

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Overview

References

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