PARP antibody

Name: PARP antibody
SKU: GTX100573_G10
Availability: BackOrder

GTX100573

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetPARP1

Overview

Supplier
GeneTex
Product Name
PARP antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.3 mg/ml
Conjugate
Unconjugated
Gene ID142
Target name
PARP1
Target description
poly(ADP-ribose) polymerase 1
Target synonyms
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PARS, PPOL, Poly-PARP, pADPRT-1, poly [ADP-ribose] polymerase 1, ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase), ADP-ribosyltransferase NAD(+), ADP-ribosyltransferase diphtheria toxin-like 1, DNA ADP-ribosyltransferase PARP1, NAD(+) ADP-ribosyltransferase 1, poly (ADP-ribose) polymerase family, member 1, poly(ADP-ribose) synthetase, poly(ADP-ribosyl)transferase, poly[ADP-ribose] synthase 1, protein poly-ADP-ribosyltransferase PARP1
Host
Rabbit
Isotype
IgG
Protein IDP09874
Protein Name
Poly [ADP-ribose] polymerase 1
Scientific Description
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Xie E, Ye Z, Wu Y, et al. The triglyceride-glucose index predicts 1-year major adverse cardiovascular events in end-stage renal disease patients with coronary artery disease. Cardiovasc Diabetol. 2023,22(1):292. doi: 10.1186/s12933-023-02028-7
Read this paper
Zhou B, Wang L, Yang S, et al. Rosmarinic acid treatment protects against lethal H1N1 virus-mediated inflammation and lung injury by promoting activation of the h-PGDS-PGD(2)-HO-1 signal axis. Chin Med. 2023,18(1):139. doi: 10.1186/s13020-023-00847-0
Read this paper
Chang HA, Ou Yang RZ, Su JM, et al. YAP nuclear translocation induced by HIF-1α prevents DNA damage under hypoxic conditions. Cell Death Discov. 2023,9(1):385. doi: 10.1038/s41420-023-01687-5
Read this paper
Wang J, Guan P, Chen Y, et al. Cyclovirobuxine D pretreatment ameliorates septic heart injury through mitigation of ferroptosis. Exp Ther Med. 2023,26(2):407. doi: 10.3892/etm.2023.12106
Read this paper
Huang C, Lin ZJ, Chen JC, et al. α-Viniferin-Induced Apoptosis through Downregulation of SIRT1 in Non-Small Cell Lung Cancer Cells. Pharmaceuticals (Basel). 2023,16(5). doi: 10.3390/ph16050727
Read this paper
Fletcher E, Miserlis D, Sorokolet K, et al. Diet-induced obesity augments ischemic myopathy and functional decline in a murine model of peripheral artery disease. Transl Res. 2023,260:17-31. doi: 10.1016/j.trsl.2023.05.002
Read this paper
Wu DD, Dai LJ, Tan HW, et al. Transcriptional upregulation of MAPK15 by NF-κB signaling boosts the efficacy of combination therapy with cisplatin and TNF-α. iScience. 2022,25(12):105459. doi: 10.1016/j.isci.2022.105459
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Calcagno G, Ouzren N, Kaminski S, et al. Chronic Hypergravity Induces a Modification of Histone H3 Lysine 27 Trimethylation at TCRβ Locus in Murine Thymocytes. Int J Mol Sci. 2022,23(13). doi: 10.3390/ijms23137133
Read this paper
Tang YC, Chang HH, Chen HH, et al. A novel NRF2/ARE inhibitor gossypol induces cytotoxicity and sensitizes chemotherapy responses in chemo-refractory cancer cells. J Food Drug Anal. 2021,29(4):638-652. doi: 10.38212/2224-6614.3376
Read this paper
Charoensaensuk V, Chen YC, Lin YH, et al. 2,3,5,4'-Tetrahydroxystilbene-2-O-β-glucoside Attenuates Reactive Oxygen Species-Dependent Inflammation and Apoptosis in Porphyromonas gingivalis-Infected Brain Endothelial Cells. Antioxidants (Basel). 2022,11(4). doi: 10.3390/antiox11040740
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PARP antibody

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