PARP3 Antibody

Cusabio

PARP3 Antibody

20

ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

PARP3

poly(ADP-ribose) polymerase family member 3

ADPRT3, ADPRTL2, ADPRTL3, ARTD3, IRT1, PADPRT-3, protein mono-ADP-ribosyltransferase PARP3, ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2, ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3, ADP-ribosyltransferase diphtheria toxin-like 3, ADPRT-3, DNA ADP-ribosyltransferase PARP3, NAD(+) ADP-ribosyltransferase 3, NAD+ ADP-ribosyltransferase 3, poly [ADP-ribose] polymerase 3, poly(ADP-ribose) synthetase-3, poly[ADP-ribose] synthase 3, poly[ADP-ribose] synthetase 3

Rabbit

IgG

Protein mono-ADP-ribosyltransferase PARP3

Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.

Human, Mouse

-20°C or -80°C

41116161