PAX5 (C2) Antibody, Rabbit Polyclonal

Biorbyt

PAX5 antibody

16

Western Blot

WB:1:1000-1:5000 WB

Research Use Only

Polyclonal

Unconjugated

PAX5

paired box 5

ALL3; B-cell lineage specific activator; BSAP; paired box homeotic gene 5; paired box protein Pax-5; paired domain gene 5; transcription factor PAX 5

Rabbit

Paired box protein Pax-5

Rabbit polyclonal to PAX5.PAX5 is a member of the paired box (PAX) family of transcription factors. The central feature of thisgene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteinsare important regulators in early development, and alterations in the expression of their genes arethought to contribute to neoplastic transformation. PAX5 is the B-cell lineage specific activator proteinexpressed at early, but not late stages of B-cell differentiation. PAX5 is also expressed in developingCNS and testis, suggesting a role of PAX5 in neural development and spermatogenesis. The PAX5gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in smalllymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas.

-20°C

12352203