PAX6 antibody
GTX113241
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPAX6
Overview
- SupplierGeneTex
- Product NamePAX6 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IP: 1:1000-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.7 mg/ml
- ConjugateUnconjugated
- Gene ID5080
- Target namePAX6
- Target descriptionpaired box 6
- Target synonymsAN, AN1, AN2, ASGD5, D11S812E, FVH1, MGDA, WAGR, paired box protein Pax-6, Aniridia 1, Aniridia 2, alternative protein PAX6, aniridia type II protein, oculorhombin, paired box 6 PAX6-12a isoform, paired box 6 PAX6A-ASdel6 isoform, paired box 6 PAX6A-ASdel6-AS7 isoform, paired box 6 PAX6A-del6 isoform, paired box 6 PAX6B-ASdel6 isoform, paired box 6 PAX6D isoform, paired box homeotic gene-6
- HostRabbit
- IsotypeIgG
- Protein IDP26367
- Protein NamePaired box protein Pax-6
- Scientific DescriptionThis gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peters anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Gilbert-Jaramillo J, Purnama U, Molnár Z, et al. Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy. Biol Open. 2023,12(4). doi: 10.1242/bio.059889Read this paper
- Chen A, Wang M, Xu C, et al. Glycolysis mediates neuron specific histone acetylation in valproic acid-induced human excitatory neuron differentiation. Front Mol Neurosci. 2023,16:1151162. doi: 10.3389/fnmol.2023.1151162Read this paper
- Fabra-Beser J, Alves Medeiros de Araujo J, Marques-Coelho D, et al. Differential Expression Levels of Sox9 in Early Neocortical Radial Glial Cells Regulate the Decision between Stem Cell Maintenance and Differentiation. J Neurosci. 2021,41(33):6969-6986. doi: 10.1523/JNEUROSCI.2905-20.2021Read this paper
- Manganas LN, Durá I, Osenberg S, et al. BASP1 labels neural stem cells in the neurogenic niches of mammalian brain. Sci Rep. 2021,11(1):5546. doi: 10.1038/s41598-021-85129-1Read this paper
- Yang SC, Liu JJ, Wang CK, et al. Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2. FASEB J. 2019,33(9):10577-10592. doi: 10.1096/fj.201800220RRRead this paper
- Xu R, Brawner AT, Li S, et al. OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome. Cell Stem Cell. 2019,24(6):908-926.e8. doi: 10.1016/j.stem.2019.04.014Read this paper
- Zhang Q, Nguyen P, Xu Q, et al. Neural Progenitor-Like Cells Induced from Human Gingiva-Derived Mesenchymal Stem Cells Regulate Myelination of Schwann Cells in Rat Sciatic Nerve Regeneration. Stem Cells Transl Med. 2017,6(2):458-470. doi: 10.5966/sctm.2016-0177Read this paper
- Chen C, Jiang P, Xue H, et al. Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells. Nat Commun. 2014,5:4430. doi: 10.1038/ncomms5430Read this paper
- Chang WF, Xu J, Chang CC, et al. SMN is required for the maintenance of embryonic stem cells and neuronal differentiation in mice. Brain Struct Funct. 2015,220(3):1539-53. doi: 10.1007/s00429-014-0743-7Read this paper
- Chen KC, Hsi E, Hu CY, et al. MicroRNA-328 may influence myopia development by mediating the PAX6 gene. Invest Ophthalmol Vis Sci. 2012,53(6):2732-9. doi: 10.1167/iovs.11-9272Read this paper




![FACS analysis of 3T3-L1 cells using GTX82816 PAX6 antibody [1C8]. Green : PAX6 Purple : negative control](https://www.genetex.com/upload/website/prouct_img/normal/GTX82816/GTX82816_20170912_FACS_w_23061322_642.webp)