WB analysis of K562 lysate using GTX88088 PBX1 antibody, Internal. Dilution : 0.5microg/ml Loading : 35microg protein in RIPA buffer
WB analysis of K562 lysate using GTX88088 PBX1 antibody, Internal. Dilution : 0.5microg/ml Loading : 35microg protein in RIPA buffer
PBX1 antibody, Internal
GTX88088
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPBX1
Overview
- SupplierGeneTex
- Product NamePBX1 antibody, Internal
- Delivery Days Customer7
- Application Supplier NoteWB: 0.3-1microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID5087
- Target namePBX1
- Target descriptionPBX homeobox 1
- Target synonymsCAKUHED; homeobox protein PBX1; homeobox protein PRL; pre-B-cell leukemia homeobox 1; pre-B-cell leukemia transcription factor 1
- HostGoat
- IsotypeIgG
- Protein IDP40424
- Protein NamePre-B-cell leukemia transcription factor 1
- Scientific DescriptionThis gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203