PBX1 antibody, Internal

GeneTex

PBX1 antibody, Internal

7

WB: 0.3-1microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

PBX1

PBX homeobox 1

CAKUHED, pre-B-cell leukemia transcription factor 1, homeobox protein PBX1, homeobox protein PRL, pre-B-cell leukemia homeobox 1

Goat

IgG

Pre-B-cell leukemia transcription factor 1

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203