PCNA antibody

GeneTex

PCNA antibody

9

IHC-P: Use at a dilution of 1/200 for 10 min at RT. No special pretreatment is required for the immunohistochemical staining of formalin/paraffin tissues. WB: Use at an assay dependent dilution. Predicted molecular weight: 31 kDa. Optimal dilutions/concentrations should be determined by the end user.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.2 mg/ml

Unconjugated

PCNA

proliferating cell nuclear antigen

ATLD2; cyclin; DNA polymerase delta auxiliary protein; proliferating cell nuclear antigen

Rabbit

IgG

Proliferating cell nuclear antigen

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]

2°C to 8°C

12352203