WB analysis of Jurkat cells using GTX52831 PDCD4 antibody at 0.2-1microg/ml.
WB analysis of Jurkat cells using GTX52831 PDCD4 antibody at 0.2-1microg/ml.
PDCD4 antibody, N-term
GTX52831
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetPDCD4
Overview
- SupplierGeneTex
- Product NamePDCD4 antibody, N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID27250
- Target namePDCD4
- Target descriptionprogrammed cell death 4
- Target synonymsH731, programmed cell death protein 4, neoplastic transformation inhibitor protein, nuclear antigen H731, programmed cell death 4 (neoplastic transformation inhibitor), protein 197/15a
- HostRabbit
- IsotypeIgG
- Protein IDQ53EL6
- Protein NameProgrammed cell death protein 4
- Scientific DescriptionThis gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Manavalan TT, Teng Y, Appana SN, et al. Differential expression of microRNA expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. Cancer Lett. 2011,313(1):26-43. doi: 10.1016/j.canlet.2011.08.018Read this paper
- Klinge CM, Riggs KA, Wickramasinghe NS, et al. Estrogen receptor alpha 46 is reduced in tamoxifen resistant breast cancer cells and re-expression inhibits cell proliferation and estrogen receptor alpha 66-regulated target gene transcription. Mol Cell Endocrinol. 2010,323(2):268-76. doi: 10.1016/j.mce.2010.03.013Read this paper
- Wickramasinghe NS, Manavalan TT, Dougherty SM, et al. Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells. Nucleic Acids Res. 2009,37(8):2584-95. doi: 10.1093/nar/gkp117Read this paper
Datasheet
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