ICC/IF analysis of cells expressing PDE5 using GTX14672 PDE5A antibody. Dilution : 1:200
ICC/IF analysis of cells expressing PDE5 using GTX14672 PDE5A antibody. Dilution : 1:200
PDE5A antibody
GTX14672
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPDE5A
Overview
- SupplierGeneTex
- Product NamePDE5A antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. ICC/IF: 1:250. IP: 1:250. ELISA: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.55-0.6 mg/ml
- ConjugateUnconjugated
- Gene ID8654
- Target namePDE5A
- Target descriptionphosphodiesterase 5A
- Target synonymsCGB-PDE, CN5A, PDE5, cGMP-specific 3',5'-cyclic phosphodiesterase, cGMP-binding cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase, cGMP-specific phosphodiesterase PDE5A2, cGMP-specific phosphodiesterase type 5A, phosphodiesterase 5A, cGMP-specific, phosphodiesterase isozyme 5
- HostRabbit
- IsotypeIgG
- Protein IDO76074
- Protein NamecGMP-specific 3',5'-cyclic phosphodiesterase
- Scientific DescriptionThis gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Tinsley HN, Gary BD, Keeton AB, et al. Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G. Mol Cancer Ther. 2009,8(12):3331-40. doi: 10.1158/1535-7163.MCT-09-0758Read this paper
Datasheet
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