
WB analysis of recombinant GFP-PDESA1 over-expressed cells treated with or without Atrial natriuretic peptide (ANP) using GTX14672 PDE5A antibody or GTX36930 PDE5A (phospho Ser 92) antibody. Dilution : 1:500
PDE5A (phospho Ser 92) antibody
GTX36930
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
TargetPDE5A
Overview
- SupplierGeneTex
- Product NamePDE5A (phospho Ser 92) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500. ICC/IF: 1:100. IP: 1:200. ELISA: 1:10000. IHC: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1-1.25 mg/ml
- ConjugateUnconjugated
- Gene ID8654
- Target namePDE5A
- Target descriptionphosphodiesterase 5A
- Target synonymsCGB-PDE, CN5A, PDE5, cGMP-specific 3',5'-cyclic phosphodiesterase, cGMP-binding cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase, cGMP-specific phosphodiesterase PDE5A2, cGMP-specific phosphodiesterase type 5A, phosphodiesterase 5A, cGMP-specific, phosphodiesterase isozyme 5
- HostRabbit
- IsotypeIgG
- Protein IDO76074
- Protein NamecGMP-specific 3',5'-cyclic phosphodiesterase
- Scientific DescriptionThis gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Li J, Bai L. The role of PDE5a in oocyte maturation of zebrafish. Gen Comp Endocrinol. 2020,286:113303. doi: 10.1016/j.ygcen.2019.113303Read this paper
- Mukohda M, Fang S, Wu J, et al. RhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity. J Clin Invest. 2019,129(6):2318-2332. doi: 10.1172/JCI123462Read this paper
- Ale-Agha N, Goy C, Jakobs P, et al. CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine. PLoS Biol. 2018,16(6):e2004408. doi: 10.1371/journal.pbio.2004408Read this paper







