ICC/IF analysis of NIH-3T3 cells using GTX00798 PDGF Receptor beta antibody [GT1140]. Red: Primary antibody Blue: DAPI
PDGF Receptor beta antibody [GT1140]
GTX00798
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetPDGFRB
Overview
- SupplierGeneTex
- Product NamePDGF Receptor beta antibody [GT1140]
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT1140
- ConjugateUnconjugated
- Gene ID5159
- Target namePDGFRB
- Target descriptionplatelet derived growth factor receptor beta
- Target synonymsActivated tyrosine kinase PDGFRB; beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140B; IBGC4; IMF1; JTK12; KOGS; NDEL1-PDGFRB; PDGFR; PDGFR1; PDGFR-1; PDGF-R-beta; PDGFR-beta; PENTT; platelet-derived growth factor receptor 1; platelet-derived growth factor receptor beta; platelet-derived growth factor receptor, beta polypeptide
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203