PE Anti-Mouse IL-10 Antibody
RD22152F
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetIl10
Overview
- SupplierReddot Biotech
- Product NamePE Anti-Mouse IL-10 Antibody
- Delivery Days Customer5
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJES5-16E3
- ConjugateRPE
- Gene ID16153
- Target nameIl10
- Target descriptioninterleukin 10
- Target synonymsCSIF; cytokine synthesis inhibitory factor; If2a; IL-; Il-10; interferon 2a; interleukin-10
- HostRat
- IsotypeIgG2b
- Scientific DescriptionL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-Oe≥, TNF-beta, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-Oe+/- synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production); and promotes mast cell proliferation in combination with IL-4.
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203