PE/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody

Reddot Biotech

PE/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

MIAP410

0.2 mg/ml

Double Conjugated

CD47

CD47 molecule

antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 glycoprotein; IAP; integrin associated protein; integrin-associated signal transducer; leukocyte surface antigen CD47; MER6; OA3; Rh-related antigen

Mouse

IgG1

CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPOe+/-, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

Human, Mouse, Rat

2°C to 8°C

12352203