Bio-Connect

PerCP/Cyanine5.5 Anti-Human CD28 Antibody

RD22143F
Reddot Biotech
TargetCD28
Product group Antibodies
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    PerCP/Cyanine5.5 Anti-Human CD28 Antibody
  • Delivery Days Customer
    5
  • Clone ID
    CD28.2
  • Gene ID940
  • Target name
    CD28
  • Target description
    CD28 molecule
  • Target synonyms
    T-cell-specific surface glycoprotein CD28; Tp44
  • Scientific Description
    CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203