Perforin antibody [N1N3]

GeneTex

Perforin antibody [N1N3]

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.37 mg/ml

Unconjugated

PRF1

perforin 1

cytolysin; HPLH2; lymphocyte pore-forming protein; P1; perforin 1 (pore forming protein); perforin-1; PFP

Rabbit

IgG

Perforin-1

The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203