PRF1 Antibody

Cusabio

PRF1 Antibody

20

ELISA

Research Use Only

Polyclonal

Unconjugated

PRF1

perforin 1

HPLH2, P1, PFP, perforin-1, cytolysin, lymphocyte pore-forming protein, perforin 1 (pore forming protein)

Rabbit

IgG

Perforin-1

Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

Human

-20°C or -80°C

41116161