PRF1 Antibody

Cusabio

PRF1 Antibody

20

ELISA

Research Use Only

Polyclonal

Unconjugated

PRF1

perforin 1

cytolysin; HPLH2; lymphocyte pore-forming protein; P1; perforin 1 (pore forming protein); perforin-1; PFP

Rabbit

IgG

Perforin-1

Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

-20°C or -80°C

12352203