ELISA analysis of phospho- and non phosho- immunogen peptide using GTX00673 PERK (phospho Ser555) antibody. P-peptide: phospho-peptide N-peptide: non-phospho-peptide Peptides concentration: 1microg/ml
PERK (phospho Ser555) antibody - Orthogonal Validated
GTX00673
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetEIF2AK3
Overview
- SupplierGeneTex
- Product NamePERK (phospho Ser555) antibody - Orthogonal Validated
- Delivery Days Customer9
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9451
- Target nameEIF2AK3
- Target descriptioneukaryotic translation initiation factor 2 alpha kinase 3
- Target synonymseukaryotic translation initiation factor 2-alpha kinase 3; pancreatic EIF2-alpha kinase; PEK; PERK; PRKR-like endoplasmic reticulum kinase; truncated eukaryotic translation initiation factor 2 alpha kinase 3; WRS
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionThe protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression. Wang IH et al., 2020 Apr 27, Cancers (Basel)Read more