IHC-P analysis of human liver tissue using GTX31910 PGC1 alpha antibody. Working concentration : 5 microg/ml
PGC1 alpha antibody
GTX31910
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPPARGC1A
Overview
- SupplierGeneTex
- Product NamePGC1 alpha antibody
- Delivery Days Customer9
- Antibody SpecificityAt least three isoforms of PPARGC1A are known to exist; this antibody only detects the longest isoform.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10891
- Target namePPARGC1A
- Target descriptionPPARG coactivator 1 alpha
- Target synonymsLEM6; ligand effect modulator-6; L-PGC-1alpha; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT; peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC1; PGC-1(alpha); PGC1A; PGC-1alpha; PGC-1-alpha; PGC-1v; PPAR gamma coactivator variant form; PPARgamma coactivator 1alpha; PPARGC1; PPARGC-1-alpha
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Mitochondrial dynamics in Angiostrongylus cantonensis-infected mouse brain. Lam HYP et al., 2021 Feb, Parasitol IntRead more