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WB analysis of rat heart (Lane 1), mouse skeletal muscle (Lane 2), rat testis (Lane 3), mouse colon (Lane 4), rat thymus (Lane 5), mouse liver (Lane 6) tissue lysates using GTX37356 PGC1 alpha antibody. Dilution : 0.5microg/ml
WB analysis of rat heart (Lane 1), mouse skeletal muscle (Lane 2), rat testis (Lane 3), mouse colon (Lane 4), rat thymus (Lane 5), mouse liver (Lane 6) tissue lysates using GTX37356 PGC1 alpha antibody. Dilution : 0.5microg/ml
WB analysis of rat heart (Lane 1), mouse skeletal muscle (Lane 2), rat testis (Lane 3), mouse colon (Lane 4), rat thymus (Lane 5), mouse liver (Lane 6) tissue lysates using GTX37356 PGC1 alpha antibody. Dilution : 0.5microg/ml

PGC1 alpha antibody

GTX37356
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPPARGC1A
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Overview

  • Supplier
    GeneTex
  • Product Name
    PGC1 alpha antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:200-1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10891
  • Target name
    PPARGC1A
  • Target description
    PPARG coactivator 1 alpha
  • Target synonyms
    LEM6; ligand effect modulator-6; L-PGC-1alpha; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT; peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC1; PGC-1(alpha); PGC1A; PGC-1alpha; PGC-1-alpha; PGC-1v; PPAR gamma coactivator variant form; PPARgamma coactivator 1alpha; PPARGC1; PPARGC-1-alpha
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UBK2
  • Protein Name
    Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
  • Scientific Description
    The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Timely expression of PGAM5 and its cleavage control mitochondrial homeostasis during neurite re-growth after traumatic brain injury.
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  • Boosting mitochondrial function and metabolism in aging female germ cells with dual ROCK/ROS inhibition.
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  • Resistance Training Diminishes Mitochondrial Adaptations to Subsequent Endurance Training.
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  • Effects of aging and long-term physical activity on mitochondrial physiology and redox state of the cortex and cerebellum of female rats.
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  • Effects of a Bacterial Infection on Mitochondrial Function and Oxidative Stress in a Songbird. Zhang Y et al., 2021 Mar-Apr, Physiol Biochem Zool
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  • Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults. Mesquita PHC et al., 2020 Aug, Physiol Rep
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  • Plumage redness signals mitochondrial function in the house finch. Hill GE et al., 2019 Sep 25, Proc Biol Sci
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  • Divergent skeletal muscle mitochondrial phenotype between male and female patients with chronic heart failure. Garnham JO et al., 2020 Feb, J Cachexia Sarcopenia Muscle
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  • Bovine Milk Extracellular Vesicles (EVs) Modification Elicits Skeletal Muscle Growth in Rats. Parry HA et al., 2019, Front Physiol
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  • Ketogenic diet increases mitochondria volume in the liver and skeletal muscle without altering oxidative stress markers in rats. Parry HA et al., 2018 Nov, Heliyon
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