WB analysis of rat heart (Lane 1), mouse skeletal muscle (Lane 2), rat testis (Lane 3), mouse colon (Lane 4), rat thymus (Lane 5), mouse liver (Lane 6) tissue lysates using GTX37356 PGC1 alpha antibody. Dilution : 0.5microg/ml
WB analysis of rat heart (Lane 1), mouse skeletal muscle (Lane 2), rat testis (Lane 3), mouse colon (Lane 4), rat thymus (Lane 5), mouse liver (Lane 6) tissue lysates using GTX37356 PGC1 alpha antibody. Dilution : 0.5microg/ml
PGC1 alpha antibody
GTX37356
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPPARGC1A
Overview
- SupplierGeneTex
- Product NamePGC1 alpha antibody
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID10891
- Target namePPARGC1A
- Target descriptionPPARG coactivator 1 alpha
- Target synonymsLEM6; ligand effect modulator-6; L-PGC-1alpha; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT; peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC1; PGC-1(alpha); PGC1A; PGC-1alpha; PGC-1-alpha; PGC-1v; PPAR gamma coactivator variant form; PPARgamma coactivator 1alpha; PPARGC1; PPARGC-1-alpha
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Effects of a Bacterial Infection on Mitochondrial Function and Oxidative Stress in a Songbird. Zhang Y et al., 2021 Mar-Apr, Physiol Biochem ZoolRead more
- Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults. Mesquita PHC et al., 2020 Aug, Physiol RepRead more
- Plumage redness signals mitochondrial function in the house finch. Hill GE et al., 2019 Sep 25, Proc Biol SciRead more
- Divergent skeletal muscle mitochondrial phenotype between male and female patients with chronic heart failure. Garnham JO et al., 2020 Feb, J Cachexia Sarcopenia MuscleRead more
- Bovine Milk Extracellular Vesicles (EVs) Modification Elicits Skeletal Muscle Growth in Rats. Parry HA et al., 2019, Front PhysiolRead more
- Ketogenic diet increases mitochondria volume in the liver and skeletal muscle without altering oxidative stress markers in rats. Parry HA et al., 2018 Nov, HeliyonRead more
- Skeletal muscle mitochondrial volume and myozenin-1 protein differences exist between high versus low anabolic responders to resistance training. Roberts MD et al., 2018, PeerJRead more
- Changes in Metabolism, Mitochondrial Function, and Oxidative Stress Between Female Rats Under Nonreproductive and 3 Reproductive Conditions. Hyatt HW et al., 2019 Jan, Reprod SciRead more
- High activity before breeding improves reproductive performance by enhancing mitochondrial function and biogenesis. Zhang Y et al., 2018 Apr 6, J Exp BiolRead more
- Physiological, mitochondrial, and oxidative stress differences in the presence or absence of lactation in rats. Hyatt HW et al., 2018 Jan 9, Reprod Biol EndocrinolRead more