Western blot analysis of extracts from COS7 cells treated with Adriamycin using Abl (Phospho-Tyr204) antibody.The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from COS7 cells treated with Adriamycin using Abl (Phospho-Tyr204) antibody.The lane on the right is treated with the antigen-specific peptide.
Phospho-ABL1 (Tyr204) Antibody
CSB-PA984556
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetABL1
Overview
- SupplierCusabio
- Product NamePhospho-ABL1 (Tyr204) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID25
- Target nameABL1
- Target descriptionABL proto-oncogene 1, non-receptor tyrosine kinase
- Target synonymsAbelson tyrosine-protein kinase 1; ABL; ABL protooncogene 1 nonreceptor tyrosine kinase; bcr/abl; bcr/c-abl oncogene protein; BCR-ABL; c-ABL; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; CHDSKM; JTK7; p150; proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; truncated ABL protooncogene 1 nonreceptor tyrosine kinase; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia viral oncogene homolog 1
- HostRabbit
- IsotypeIgG
- Protein IDP00519
- Protein NameTyrosine-protein kinase ABL1
- Scientific DescriptionNon-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like WASF3 (involved in branch formation); ANXA1 (involved in membrane anchoring); DBN1, DBNL, CTTN, RAPH1 and ENAH (involved in signaling); or MAPT and PXN (microtubule-binding proteins). Meyn MA, et al. (2006) J Biol Chem 281, 30907-16 Steen H, et al. (2003) Mol Cell Proteomics 2, 138-45 Salomon AR, et al. (2003) Proc Natl Acad Sci U S A 100, 443-8
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203