Western blot analysis of extracts from 3T3 cells untreated(lane 1) or treated with Hydroxyurea(lane 2) using Cdc25B(Phospho-Ser149) Antibody.
Western blot analysis of extracts from 3T3 cells untreated(lane 1) or treated with Hydroxyurea(lane 2) using Cdc25B(Phospho-Ser149) Antibody.
Phospho-Cdc25b (Ser149) Antibody
CSB-PA905252
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityMouse, Rat
TargetCdc25b
Overview
- SupplierCusabio
- Product NamePhospho-Cdc25b (Ser149) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID12531
- Target nameCdc25b
- Target descriptioncell division cycle 25B
- Target synonymsAI604853; dual specificity phosphatase Cdc25B; M-phase inducer phosphatase 2
- HostRabbit
- IsotypeIgG
- Protein IDQ9DBN8
- Protein NameCdc25b protein
- Scientific DescriptionCdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. Li G, et al. (2010) Retrovirology.7:59. Wang Z,et al. (2010) BMC Cancer.10:233. Lucci MA,et al. (2010) Cell Oncol.32(5-6):361-72.
- ReactivityMouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203