Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using PKR(Phospho-Thr451) Antibody(left) or the same antibody preincubated with blocking peptide(right).
Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using PKR(Phospho-Thr451) Antibody(left) or the same antibody preincubated with blocking peptide(right).
Phospho-EIF2AK2 (Thr451) Antibody
CSB-PA035578
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetEIF2AK2
Overview
- SupplierCusabio
- Product NamePhospho-EIF2AK2 (Thr451) Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5610
- Target nameEIF2AK2
- Target descriptioneukaryotic translation initiation factor 2 alpha kinase 2
- Target synonymsdouble stranded RNA activated protein kinase; eIF-2A protein kinase 2; EIF2AK1; interferon-induced, double-stranded RNA-activated protein kinase; interferon-inducible elF2alpha kinase; LEUDEN; P1/eIF-2A protein kinase; p68 kinase; PKR; PPP1R83; PRKR; protein kinase R; protein kinase, interferon-inducible double stranded RNA dependent; protein phosphatase 1, regulatory subunit 83; tyrosine-protein kinase EIF2AK2
- HostRabbit
- IsotypeIgG
- Protein IDP19525
- Protein NameInterferon-induced, double-stranded RNA-activated protein kinase
- Scientific DescriptionFollowing activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection. Ingrid K. Ruf, et,al. (2005) J. Virol ; 79: 14562 - 14569. Christy M. Hebner,et,al. (2006) J. Gen. Virol ; 87: 3183 - 3193. Rika van Huizen, et,al. (2003) J. Biol. Chem ; 278: 15558 - 15564.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203