PKR antibody

GeneTex

PKR antibody

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:521. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

EIF2AK2

eukaryotic translation initiation factor 2 alpha kinase 2

DYT33, EIF2AK1, LEUDEN, PKR, PPP1R83, PRKR, interferon-induced, double-stranded RNA-activated protein kinase, P1/eIF-2A protein kinase, double stranded RNA activated protein kinase, eIF-2A protein kinase 2, interferon-inducible elF2alpha kinase, p68 kinase, protein kinase R, protein kinase RNA-regulated, protein kinase, interferon-inducible double stranded RNA dependent, protein phosphatase 1, regulatory subunit 83, tyrosine-protein kinase EIF2AK2

Rabbit

IgG

Interferon-induced, double-stranded RNA-activated protein kinase

EIF2AK2 is a protein serine/threonine kinase that acquires enzymatic activity following autophosphorylation, a process mediated by double-stranded RNA (dsRNA). Activation of EIF2AK2 allows the kinase to phosphorylate its natural substrate, the alpha subunit of eukaryotic protein synthesis initiation factor-2 (EIF2-alpha; MIM 603907), leading to the inhibition of protein synthesis (summary by Kuhen et al., 1996 [PubMed 8812437]).[supplied by OMIM]

Human

-20°C or -80°C,2°C to 8°C

12352203