
Western blot analysis of extracts from Mouse brain tissue using HDAC3 (Phospho-Ser424) Antibody.The lane on the left is treated with the antigen-specific peptide.
Phospho-HDAC3 (Ser424) Antibody
CSB-PA170084
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetHDAC3
Overview
- SupplierCusabio
- Product NamePhospho-HDAC3 (Ser424) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8841
- Target nameHDAC3
- Target descriptionhistone deacetylase 3
- Target synonymsHD3; histone deacetylase 3; KDAC3; RPD3; RPD3-2; SMAP45
- HostRabbit
- IsotypeIgG
- Protein IDO15379
- Protein NameHistone deacetylase 3
- Scientific DescriptionResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203